【兽药名称】通用名:头孢噻呋钠
商品名:拜邦第三代进口头孢
【性 状】本品为白色或微黄色冻干粉末。
【药理作用】本品系半合成的β-内酰胺类抗生素,为全球第一个畜禽 专用的第三代头孢菌素。其可与细胞膜上的青霉素结合蛋白(PBP)结合,阻碍细胞壁粘肽的合成,造成细胞壁不能交联而导致细菌破裂死亡。该药对各种革兰氏阳菌、革兰氏阳性菌包括产β-内 酰胺菌均有效,敏感菌有沙门氏菌、大肠杆菌、巴氏杆菌、嗜血杆菌、链球菌、葡萄球菌、坏死梭菌、放线菌等。且其杀菌作用远比庆大霉素、氨苄西林、林可霉素、壮观霉素等其它抗生素强大。
【药理特点】
1、在感染组织中的含量比非感染组织高2-4倍,注射后吸收迅速,1小时内血药浓度达到峰值,有利于更好的发挥药物用。
2、有效血浓度维持时间长达72小时,低剂量使用,且在体内生成的一级代谢产物脱呋喃 甲酰头孢噻呋同样具有强大的抗菌作用,因而具有后效性。
3、安全性高。本品作用机理为阻断细菌细胞壁的合成,而畜禽没有细胞壁,故而安全性高,没有任何不良反应。
4、彻底解决兽药残留问题。
【适 应 症】用于鸡大肠杆菌、沙门氏菌感染等,猪的细菌性呼吸道感染。
【主 治】鸡:防治鸡大肠杆菌病、白痢、副伤寒等,减少雏鸡早 期死亡,7日内死亡率显著下降,提高机体免疫力和存活率。
鸭:治疗鸭浆膜炎、鸭肠道病及各类细菌病有独特疗效。
猪:治疗猪萎鼻、副嗜血杆菌、猪胸膜肺炎放线杆菌、多杀性巴 氏杆菌、猪沙门氏杆菌、猪链球菌、肺炎球菌引起的呼吸道病。
牛:用于治疗细菌引起的呼吸道病(运输热、肺炎)、腐蹄病、乳房炎、犊牛腹泻、犊牛脐炎。
犬:用于大肠杆菌和奇异变形菌引起的泌尿道感染、消化道感染。
【用法用量】注射或饮水:1日龄雏鸡:将0.5g本品稀释于1000毫升马立克疫苗或 稀释液中,用带7号针头的连续注射器颈部皮下注射0.2毫升,即每只鸡苗注射量为0.1毫克的本品,本品至少可用5000只鸡。大鸡和鸭:(对鸭浆膜炎等巴氏杆菌有特效)每公斤体重肌肉注 射1毫克。其他:每公斤体重肌肉注射一次量:猪3-5mg、牛1.1-2.2mg、一日一次;犬皮下注射每公斤体重一次量2.2mg一日一次。
【注意事项】用稀释液或注射用水现用现配,稀释后的溶液2-8冷藏可保存7天,室温可保存12小时,冷冻保存8周,药效颜色变化和稀释后轻微混浊不影响效果。
【规 格】1.0g/瓶/X10瓶/盒
【贮 藏】常温保存两年。
美国拜邦生物科技集团有限公司
common name: ceftiofur sodium
Commodity name: Bai Bang
import of third generation
this product is white or yellow freeze-dried powder.
the pharmacological effects of strains of semi-synthetic beta-lactam antibiotics, as the world"s first livestock and poultry for third generation cephalosporin. The cell membrane of penicillin binding protein (PBP) combined with block, synthesis of peptidoglycan in cell wall, resulting in cell wall cross-
linking caused the breakdown of the death of bacteria can not. The drug against various gram positive bacteria, gram positive bacteria, including production of beta-lactam bacteria are effective, sensitive strains of Salmonella, Escherichia coli, Pasteurella, Haemophilus influenzae, Streptococcus, Staphylococcus, Fusobacterium necrophorum, actinomycetes. And the bactericidal effect than gentamicin, ampicillin, lincomycin, spectinomycin and other antibiotics strong.
the pharmacological characteristics
1, than the content in the infected tissue infected 2-4 times higher tissue after injection, rapid absorption, peak plasma concentrations achieved within 1 hours, will make better use of drug use.
2, effective blood concentration up to 72 hours, low dose, and in primary metabolites generated from furoyl ceftiofur also has strong antibacterial effect, thus has the aftereffect.
3, high safety. The mechanism for blocking synthesis of bacterial cell walls, and livestock and no cell wall, therefore, high safety, no adverse reaction.
4, solve the problem of veterinary drug residues.
for Escherichia coli, Salmonella infection, bacterial respiratory tract infection in pigs.
chicken: prevention and control of Chicken Colibacillosis, diarrhea, paratyphoid fever, reduce the early death of chicks, 7 days mortality decreased significantly, improve immunity and survival rate.
Duck: a unique effect in treatment of serositis of duck, duck intestinal disease and various bacterial disease.
Pig: treatment of pig wilt nasal, Haemophilus, Actinobacillus pleuropneumoniae, multocida Pakistan"s bacillus, Salmonella, Streptococcus suis in pigs, pneumococcal respiratory disease.
Cow: for the treatment of bacterial respiratory tract disease (heat transport, pneumonia), foot rot, mastitis, calves omphalitis, diarrhea in calves.
Dog: for digestive tract infection, Escherichia coli and Proteus bacteria causing urinary tract infection.
injection or drinking water: 1 day-old chicks: will 0.5g the diluted in 1000 ml of the Marek vaccine or diluent, with No. 7 pinhead continuous syringe neck subcutaneous injection of 0.2 ml, namely each chicks injection volume was 0.1 mg of this product, this product can be used at least 5000 chickens. Chicken and duck: (on the effects of duck serositis, Pasteurella) muscle injection of 1 mg per kilogram of body weight. Other: per kg body weight an intramuscular injection of pig, cattle: 3-5mg 1.1-2.2mg, once a day; canine subcutaneous injection at a dose of 2.2mg per kg body weight once a day.
with the dilution liquid or water for injection by using now, the diluted solution 2-8 refrigerator can be stored for 7 days at room temperature, can be preserved for 12 hours, 8 week of cryopreservation effect, color change and diluted slightly turbid does not affect the results.
1.0g/ bottle /X10 bottle / box
stored at room temperature for two years.
The United States of America thanks to the state of Biological Technology Group Co., Ltd.
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